Analysing supra gingival biofilm formation

We are investigating the gingival bacterial colonization and the role of bacterial virulence factors for the epithelial (innate) immune response during biofilm formation using molecular and biochemical tools. The community structures, colonization profiles and the functional diversity of microorganisms involved in the formation of biofilms are analysed over a 21 day period applying next generation pyro-sequencing. Simultaneously the clinical inflammation processes as well as the epithelial immune response are analysed in close collaboration with Dr. Jörg Eberhardt (Medizinische Hochschule Hannover). (funded by the DFG)

Analysing supra gingival biofilm formation